Magnesium glycinate cures depression

My short term memory problems, difficulties concentrating, slowed thinking, confusion, mental fatigue and trouble speaking have almost completely  disappeared since I went off of antidepressants and starting taking magnesium bis-glycinate 200 supplements.

As I said in my last blog, weaning off of prescription drugs was a slow process and it was an adjustment. However, my salvation during this whole process has been taking magnesium supplements. I have taken 200 mgs of magnesium once or twice a day for the last 3 months. I was able to purchase this CanPrev products from Nutraways on Lonsdale Avenue in North Vancouver and found this type of magnesium at Choices Market. Note the type of magnesium is critical to absorption.

As promised, I plan to write further blogs to provide you with the literature about antidepressants and natural alternatives. These blogs will come in time. In the meantime, be sure to read this short abstract published by the U.S. National Institute of Health. It will alert you to the reason depression is so widespread in North America. And you will learn that I am not alone in receiving substantial benefit from magnesium. http://www.ncbi.nlm.nih.gov/pubmed/16542786

DRUGS CAN CAUSE CNS LUPUS-LIKE SYMPTOMS

WAS THIS AN UNIQUE STORY?

Not at all!

While I think my experience has been unusual, I know that it is not unique.

My recent google search for CNS lupus symptoms brought me to the Lupus Foundation of America website. The headline read “drugs used to treat lupus can cause side effects that are similar to the symptoms of CNS lupus.” It encourages people to consult with a neurologist who can determine if the drugs rather than lupus could be the cause of the problems.

 DRUGS THAT CAN CAUSE CNS LUPUS-LIKE SYMPTOMS

NSAIDS (non- steroidal anti-inflammatory drugs)	Celebrex, ibuprofen, and naproxen
Antimalarial drugs	plaquenil and hydroxycholoroquine
Corticosteroids	Prednisone
Hypertensive drugs	blood pressure medications like beta blockers

http://www.lupus.org/webmodules/webarticlesnet/templates/new_donatenow.aspx?articleid=2323&zoneid=43

Most surprising is that antidepressant drugs are not included in their list. I think this is an oversight.

But I am not naïve. I have to say that I have excellent doctors - they are world renowned doctors at the top of their fields.  My neurologist is a graduate of the Harvard University. And if he missed this, then most other doctors are also probably not aware of the side effects of antidepressants.

Perhaps doctors are in the dark because pharmaceutical companies do not publicize the problems with their cash cows?

I have done a lot of reading about antidepressants recently. There is considerable evidence about how ineffective these drugs are and just how harmful they can be. Certainly, my story demonstrates this.

My upcoming blogs are going to focus on the research which calls into question the effectiveness of antidepressants. I know you will be shocked to learn that antidepressants actually increase the risk of suicide. 

After that, I am going to share information about better, more natural ways that have helped me deal with symptoms of depression. 

 

ANTIDEPRESSANTS CAUSED MY ZOMBIE STATE

This blog explains why I had a serious reaction to taking antidepressants as described in my last blog, the Wakeup Call.

When I researched the internet and reviewed my cocktail of drugs, I realized that taking three drugs for depression at one time could cause serious problems.  I was taking Prozac and Trazodone at the same time. I was also taking clonazepam at bedtime for sleep. Although I did not realize it at the time this was the drug I needed to calm me from the side effects of the antidepressants.

The literature stated that there is a serious drug interaction between Trazodone and Prozac. http://www.drugs.com/drug-interactions/prozac-with-trazodone-1115-648-2228-0.html

The doctors and the pharmacists I have talked to seem to know this but they don’t really believe it. I have interviewed many pharmacists since I decided to gather information about antidepressants. Unfortunately, it seems rather common place to prescribe both of these drugs together.

There seems to be a lack of awareness of the effect of serotonin syndrome.  This condition occurs when there is too much of the neurotransmitter serotonin and in its most serious form it can lead to death. (Coincidentally, one of the treatments for this condition is taking a sedative like clonazepam so I guess it was lucky that I was taking this medication at the same time). Some of the symptoms of this syndrome which I have experienced include confusion, hypomania (slow thinking), tremor, muscle spasms, uncoordinated movement, high heart rate and high blood pressure.

As I have written in my previous blogs, I have almost stopped taking all antidepressants. Now I only take one quarter of the previous dose of trazodone and I plan to stop it completely soon.  With my oldest sister being critically ill, I have continued this drug as a crutch to deal with a high stress level and to help me sleep at night. I was originally prescribed this drug by the University of British Columbia Sleep Clinic to control periodic limb movement which affects my sleep at night.

In the last week, though I have been able to get back to playing tennis and I probably don’t need the drug to sleep at night.  I have also stopped taking the low dose of clonazepam which helped me to get to sleep quickly.

Getting off antidepressants after about 15 years has been a challenge! I have gone through withdrawal. I have felt moody, unwell, muscle pain, experienced panic reactions and had some trouble sleeping. I gradually stopped taking the medication over a few months. I had to set my own schedule because this is not something that any doctor was recommending.

Natural alternatives such as magnesium, and vitamin B6 are helping me to prevent depression. I am able to experience my emotions rather than just feeling numb. I have escaped the zombie state and I am thrilled!

THE WAKEUP CALL

As I said in my last blog, I was really close to being prescribed another drug for my worsening CNS symptoms. And then I had a serious reaction to wellbutrin. It was a wakeup call!

I doubt I would have stopped antidepressants and regained my mind if I had not gone through the experience of feeling suicidal. This feeling set off alarm bells in my head.  It happened on a weekend so I was left to my own devices. This is good because it is unlikely I would have got answers from my doctors or pharmacists.

 I got on the internet and found out that the drug could be causing the symptoms – suicidal thoughts, confusion, short term memory problems, and the lack of coordination. I also learned that someone with a family history of bipolar should not have been prescribed the drug.

This shocked me to the core! I then realized that I had to verify everything to do with my healthcare. I started to look at all of the prescriptions I was taking.  It was easy to find relevant prescription drug information on the internet and I would highly recommen

d visiting www.drugs.com and the US government website www.fda.gov/drugs.  I could not believe that the doctors and pharmacists did not know this information. The individual drug interactions are known. Out of 8 drugs, I had 5 serious drug interactions going on. But this is a whole other story for another blog.

It was my review of all of the drug interactions that altered my medication plan. One of my biggest risks of having CNS lupus (inflammation of the blood vessels in my brain) is having a stroke. One of the drugs I am taking is plavix which makes my blood less sticky and less likely to cause a blood clot.  Can you imagine my dismay when I found out that this drug has been rendered useless because I was also taking Prozac, an anti-depressant? Thousands of dollars down the drain over 8 years, unmitigated risk and not one professional pointed this out.

After bringing this to the attention of my doctors, they suggested that there was another antidepressant that I could take that would not interfere with the plavix. When I went to pick up the prescription from the pharmacist, he cautioned me to stop the Prozac for a period of 6 weeks before starting another antidepressant. I heeded his advice since I was not eager to repeat the suicidal idealization experience -besides this was going to be the third differenct antidepressant taken in just over 3 months.

About the same time, I spoke to a tennis friend who is a pharmacist. He said that I needed to stop taking most of the drugs in order to get over all of the drug interactions.  He said that normally someone is hospitalized and taken off all of the drugs. Then they are reintroduced say 2 rather than 8 medications.

Hospitalization was not an option. I knew I had to wean myself off of the antidepressants. It would have been best if I had received advice from a psychiatrist but I was several months away from being able to see one. I planned and executed my own withdrawal scheme. My experience of withdrawal is described in my next blog - Antidepressants Caused my Zombie State.

A DECADE OF FOG

A DECADE OF FOG

As I said in my last blog, I have just recently recovered from a decade in a fog. And I feel great!

Contrast this to a decade ago when I was a prescribed a serious overdose of antidepressants – more than enough to knock out even a depressed elephant. 60 mgs of Prozac and 150 mgs of trazadone  – all of this for a reasonably slender woman. The studies show that 20 mgs of Prozac treats most people with major depressive disorder. http://www.rxlist.com/prozac-drug/indications-dosage.htm.

The prescription was written to treat depression which could cause difficulty concentrating, and memory problems. It was believed that my cognitive problems could be caused by depression rather than CNS lupus. I never had symptoms of crying, loss of enjoyment of favourite activities, or sadness.  However, I was started on a cocktail of drugs that sent me into a downward spiral.  But then things got too complicated to be able to distinguish what was causing which symptoms.

 I had other difficulties like trouble speaking, clumsiness, confusion, fatigue, headaches, pain and sleeping 12 hours a day. And the numerous brain lesions showing on numerous MRIs proved that there was an inflammatory reaction going on within my brain. Thus it was not just depression that was causing the cognitive difficulties.

Over the last decade I slowly cut back on the antidepressants and my cognitive functioning started to improve. At the same time, I took chemotherapy drugs which stopped the development of new lesions on my brain. The drugs taken to combat my overactive immune system were credited with my improving health or, at least, no further deterioration.

But then my brain started to go on another downward trajectory last September. This happened when I replaced one antidepressants medication with another.  I started to take another anti-depressant called wellbutrin. It was billed as causing fewer sexual side effects and I had finally clued into ones sex life does not go on forever so I should pay more attention to it. Once again I was given too high a dose of antidepressants. I was prescribed three 100 mg of the slow release Wellbutrin to take once a day. According to all the published sources this exceeded the maximum dose at one time. Even 300 mgs spread out throughout the day was a dose that sets off a warning for US pharmacists.

As the fall progressed, I got worse. My short term memory was getting dangerously impaired. I could not keep track of who was serving in a tennis game, not to mention the score. When I could not recognize the host of a neighbourhood party a week later, I thought a room on the Alzheimer floor at the local care facility would soon be my new home. I fared very poorly playing brain games with my young nephew. But it was the neuropsychiatric assessment which proved my brain capacity was sliding when I performed worse than the previous test a few years before. 

At this point, my rheumatologist was evaluating whether to place me on a new drug to treat the worsening CNS lupus symptoms. Thankfully, he was being cautious since the new biologic drug, he had in mind, could be fatal. And he needed to line up the proof that I was still not better despite having taken cyclophosphamide, Imuran and methotrexate. He needed to complete paperwork to justify to the Medical Services Plan why I needed to receive this very expensive drug.

You probably have heard about the new biologic drugs available to treat people with autoimmune diseases.  You may have seen the television advertisements that list a zillion side effects and you conclude that someone must be desperate to even consider taking such a drug. Well, yes I was at this point. It seemed like it was either a new drug or soon I would be checking into my new home – one of the locked units for the demented patients at a care facility.

In November, my rheumatologist was waiting to hear from my neurologist. And my neurologist was waiting to hear from the psychiatrist who I had asked to see. However, this neurologist/psychiatrist specialist in CNS lupus was not accepting new patients. It then fell onto my family physician to make a referral to another psychiatrist. She said that it would take more than 6 months before I could get a referral.

Then the precipitating event happened. To find out more read the next blog – The Wakeup Call.   

A DECADE LATER

58 years old! It has been a decade since I was first diagnosed with lupus. I have fared well. I can play tennis, cook a holiday meal, dance to the golden oldies, decipher fact from fiction and write blogs. I am doing better than I was a decade ago and finally emerging from a semi-coma. Well, not literally but that is what it feels like.

I can talk easily again – at a regular speed and at an audible level. The speed of my thinking has increased so significantly I have had to ask friends whether they think I am becoming manic. They have assured me that I have just become normal again.  In comparison to a few months ago, I am quick with the wit, aware of my surroundings, and more perceptive of my feelings and those of the people around me.  I am interrupting people less because I can remember what I want to say until after the other person has finished speaking.  

Being able to experience emotions again does come with a downside.  It does hurt more when a “friend” tells you that she thinks that you are a hypochondriac.  Doesn’t she understand that all of these weird health problems happen to someone with lupus? And when your sister and children blame you for their problems, you feel the rejection and anguish.

Experiencing grief and anger is so much more intense.  My blood boils because my oldest sister has been medically neglected in a “care facility” - this has literally raised my blood pressure. And my discomfort at being hoodwinked into believing the prescription drugs provided benefits that were worth sacrificing the joy of sex for so many years is strong. There is safety in being drugged into “unfeeling” but it means that you miss out on the essence of life.

And then there is the perception of time. This seems paradoxical but time has slowed down. Maybe it is because I have so many more hours in the day because I am not sleeping and I am so more efficient in everything I do. The thought of being bored has even crept into my mind.  

So for now, I will go back to my blogging. I will try to ignore that most of the people I know don’t want to be hear about healthy living.  I will attempt to tone down my level of proof provided to augment my arguments and let my sources speak for themselves

My next blog discusses how I emerged from what was thought to be lupus fog.